ארה״ב
AHK-Cu
פפטידים בודדים
$49.99$0.50/mg
COA בתיקתוצרת ארה״ב
פפטידים בודדים
Kisspeptin
$59.99$6.00/mg
תיאור
Kisspeptin-10 הוא דקאפפטיד סינתטי (Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2). מסופק כאבקה ליופילית (מיובשת בהקפאה) בבקבוקונים אטומים. לכל אצווה תעודת אנליזה (COA) משלה, שנפתחת בסריקת קוד ה-QR שעל התווית. לשימוש מחקרי במעבדה בלבד. לא לשימוש בבני אדם או בבעלי חיים.
לשימוש מחקרי בלבד. לא לשימוש בבני אדם או בבעלי חיים. לא נועד לאבחון, טיפול, ריפוי או מניעה של מחלה כלשהי.
Research profile
Kisspeptin-10 research profile
Kisspeptin-10 is the C-terminal decapeptide of kisspeptin-54 (metastin), the peptide products of the KISS1 gene. It is the minimal sequence that activates the GPR54 (KISS1R) receptor. Metastin was isolated from human placenta by Ohtaki and colleagues at Takeda in 2001.
Specifications
- Sequence
- Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 (YNWNSFGLRF-NH2)
- Molecular formula
- C63H83N17O14
- Molecular weight
- ≈ 1302.5 g/mol
- CAS number
- 374675-21-5
- גודל
- 10 mg per vial
- Form
- Lyophilized powder, sealed vial
- Storage
- Keep sealed, protected from light and moisture; follow the label
- Testing
- HPLC purity and mass spectrometry identity, per lot. Scan the QR code on the vial for the certificate of analysis.
Published research
- Discovery and metastasis: CHO cell migration and B16-BL6 melanoma lung metastasis in mice (Ohtaki et al., Nature, 2001); kisspeptins named as GPR54 ligands (Kotani et al., J Biol Chem, 2001).
- Chemotaxis signalling: Kp-10/GPR54 and CXCR4-mediated migration (Navenot et al., Cancer Res, 2005).
- GnRH neuron physiology in mouse brain slices (Pielecka-Fortuna et al., Endocrinology, 2008).
- Reproductive-axis physiology studies (George et al., J Clin Endocrinol Metab, 2011).
Frequently asked questions
What is the difference between kisspeptin-10 and kisspeptin-54?
Kisspeptin-54 (metastin) is the full 54-residue peptide; kisspeptin-10 is its last 10 residues, the minimal sequence that activates GPR54.
Why is it called metastin?
The KISS1 gene was first known as a metastasis suppressor.
How do I verify my lot?
Scan the QR code on the vial. It opens the certificate of analysis for that lot, with HPLC purity and the mass spectrometry identity result.
For laboratory research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease. Literature references are provided for scientific context and do not describe this product's suitability for any use.
עוד בפפטידים בודדים
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