ארה״ב
AHK-Cu
פפטידים בודדים
$49.99$0.50/mg
COA בתיקתוצרת ארה״ב
פפטידים בודדים
ARA 290
$69.99
תיאור
ARA 290 הוא פפטיד סינתטי בן 11 חומצות אמינו, הנגזר מאזור סליל B של אריתרופויאטין. מסופק כאבקה ליופילית (מיובשת בהקפאה) בבקבוקונים אטומים. לכל אצווה תעודת אנליזה (COA) משלה, שנפתחת בסריקת קוד ה-QR שעל התווית. לשימוש מחקרי במעבדה בלבד. לא לשימוש בבני אדם או בבעלי חיים.
לשימוש מחקרי בלבד. לא לשימוש בבני אדם או בבעלי חיים. לא נועד לאבחון, טיפול, ריפוי או מניעה של מחלה כלשהי.
Research profile
ARA-290 research profile
ARA-290 (cibinetide) is an 11-residue peptide designed from the aqueous face of helix B of erythropoietin. It was built to engage the EPOR/CD131 "innate repair receptor" without stimulating red-cell production, and was described by Brines, Cerami and colleagues in 2008.
Specifications
- Sequence
- pGlu-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser (pE-EQLERALNSS)
- Molecular formula
- C51H84N16O21
- Molecular weight
- ≈ 1257.3 g/mol
- CAS number
- 1208243-50-8
- Form
- Lyophilized powder, sealed vial
- Storage
- Keep sealed, protected from light and moisture; follow the label
- Testing
- HPLC purity and mass spectrometry identity, per lot. Scan the QR code on the vial for the certificate of analysis.
Published research
- Tissue-protection models: rat spinal cord cultures, rodent stroke, rat diabetic retinal edema, sciatic nerve compression and mouse renal ischemia-reperfusion, without erythropoietic activity (Brines et al., PNAS, 2008).
- Small-fiber neuropathy: Phase 2 placebo-controlled study (Brines et al., Mol Med, 2014).
- Corneal nerve fibres: Phase 2b study in sarcoidosis-associated small nerve fibre loss (Culver et al., Invest Ophthalmol Vis Sci, 2017).
Frequently asked questions
What is cibinetide?
The international nonproprietary name for ARA-290.
What does pGlu mean?
Pyroglutamate, a cyclized N-terminal glutamine or glutamate residue.
How do I verify my lot?
Scan the QR code on the vial. It opens the certificate of analysis for that lot, with HPLC purity and the mass spectrometry identity result.
For laboratory research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease. Literature references are provided for scientific context and do not describe this product's suitability for any use.
עוד בפפטידים בודדים
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