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Single Peptides
Selank
$39.99
Description
Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) derived from tuftsin. Supplied as a lyophilized powder in sealed vials. Each batch has its own certificate of analysis (COA), which opens when you scan the QR code on the label. For laboratory research use only. Not for human or veterinary use.
Research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease.
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Research profile
Selank research profile
Selank is a synthetic heptapeptide, Thr-Lys-Pro-Arg-Pro-Gly-Pro. It was designed by extending tuftsin (Thr-Lys-Pro-Arg), a naturally occurring tetrapeptide, with a Pro-Gly-Pro sequence that is associated with greater resistance to peptidase breakdown. It was developed at the Institute of Molecular Genetics of the Russian Academy of Sciences.
Specifications
- Sequence
- Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP)
- Molecular formula
- C33H57N11O9
- Molecular weight
- ≈ 751.9 g/mol
- CAS number
- 129954-34-3
- Size
- 10 mg per vial
- Form
- Lyophilized powder, sealed vial
- Storage
- Keep sealed, protected from light and moisture; follow the label
- Testing
- HPLC purity and mass spectrometry identity, per lot. Scan the QR code on the vial for the certificate of analysis.
Published research
- Origin: Selank is a tuftsin analog. Tuftsin is a fragment of the Fc domain of the immunoglobulin G heavy chain.
- GABAergic signaling: published rodent and in vitro studies have examined Selank as an allosteric modulator of GABA-A receptor ligand binding.
- Gene expression: several papers report changes in expression of genes involved in GABAergic neurotransmission in rodent brain tissue after Selank exposure.
- Behavioral models: Selank has been studied in rodent stress and behavioral models, often alongside reference compounds.
Frequently asked questions
What is the sequence of Selank?
Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP), a heptapeptide with a molecular weight of about 751.9 g/mol.
How is Selank related to tuftsin?
Selank contains the tuftsin sequence Thr-Lys-Pro-Arg, extended with Pro-Gly-Pro at the C-terminus.
How do I verify my lot?
Scan the QR code on the vial to open the certificate of analysis for that lot, with HPLC purity and mass spectrometry identity.
For laboratory research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease. Literature references are provided for scientific context and do not describe this product's suitability for any use.
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