AHK-Cu
AHK-Cu is the copper(II) complex of the tripeptide L-alanyl-L-histidyl-L-lysine. Supplied as a lyophilized powder in sealed vials. For laboratory research use only. Not for human or veterinary use.
AHK-Cu research profile
AHK-Cu is the copper(II) complex of the tripeptide L-alanyl-L-histidyl-L-lysine (AHK). It is a close structural analog of GHK-Cu: the N-terminal glycine is replaced by alanine, while the His-Lys copper-binding motif is kept.
Specifications
- Sequence
- Ala-His-Lys (AHK), copper(II) complex
- Molecular formula
- C15H24CuN6O4 (complex); C15H26N6O4 (AHK)
- Molecular weight
- ≈ 415.9 g/mol (complex); 354.4 g/mol (AHK)
- Size
- 100 mg per vial
- Form
- Lyophilized powder, sealed vial
- Appearance
- Blue to violet powder (copper complex)
- Storage
- Keep sealed, protected from light and moisture; follow the label
- Testing
- HPLC purity and mass spectrometry identity, per lot. Scan the QR code on the vial for the certificate of analysis.
Published research
- Hair follicle cell culture: a tripeptide-copper complex was studied for its effect on cultured human hair follicles in vitro (Pyo et al., Arch. Pharm. Res., 2007).
- Dermal papilla cells: AHK and dimeric AHK derivatives were evaluated for proliferation of primary human dermal papilla cells in culture (Jeong, Park & Kim, Bull. Korean Chem. Soc., 2021).
- Structure–activity: AHK-Cu is often studied alongside GHK-Cu to compare how the N-terminal residue affects copper binding and activity in cell models.
Frequently asked questions
What is the difference between AHK-Cu and GHK-Cu?
Only the first amino acid differs: AHK-Cu has alanine where GHK-Cu has glycine. Both keep the His-Lys copper-binding motif. Our guide compares the two in more detail.
How much AHK-Cu is in each vial?
Each vial contains 100 mg of lyophilized AHK-Cu.
How do I verify my lot?
Scan the QR code on the vial to open the certificate of analysis for that lot, including HPLC purity and mass spectrometry identity.
For laboratory research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease. Literature references are provided for scientific context and do not describe this product's suitability for any use.
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